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Such conduction abnormalities are often treated with chronic subpulmonary LV (i.e., univentricular) pacing. However, pacing-induced dyssynchrony is a well-known phenomenon that worsens sRV dysfunction and contributes to sRV failure. Indeed, LV pacing is a risk factor for progressing sRV dysfunction in cc-TGA patients .
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Approximately 50% of the patients with heart failure have normal, or near-normal left ventricular (LV) systolic heart function with a LV ejection fraction ≥ 50% and a LV end-diastolic volume index < 97 mL/m 2. These patients are described as having heart failure with preserved ejection fraction (HFpEF).
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